Ekaterina A. Trifonova
Ekaterina A. Trifonova, PhD, Researcher Laboratory of Evolution genetics, Research Institute of Medical Genetics, Tomsk NRMC; Associate Professor of Biology and Genetics, Siberian State Medical University (Tomsk, Russia).Contact details
e-mail: ekaterina.trifonova@medgenetics.ruPhone: 8 (3822) 51-33-34
Fax: 8 (3822) 51-37-44
Education
2011-2013: genetic residency at Siberian State Medical University (Tomsk, Russia).
2009-2010: internship in the field of clinical laboratory diagnostics, Siberian State Medical University (Tomsk, Russia).
2006-2009: PhD in Genetics, Laboratory of Evolution genetics, Research Institute of Medical Genetics (Tomsk, Russia).
2000-2006: Medical-Biological Faculty of Siberian State Medical University (Tomsk, Russia).
Work experience
2017 – Present: Assistant Professor, Department of Biology and Genetics, Siberian State Medical University (Tomsk, Russia).
2009 – Present: Researcher, Laboratory of Evolution genetics, Research Institute of Medical Genetics, Tomsk NRMC
2014-2015: Senior Researcher, Laboratory for Translational Cellular and Molecular Biomedicine, Tomsk State University
2006 – 2009: Technician, Laboratory of Evolution genetics, Research Institute of Medical Genetics, SB RAMS
Research Interests
The main research interests include studies in the field of common diseases genomics and transcriptomics. Her current research focuses on the development of molecular bases and method of predicting the risk of the great obstetrical syndromes (preeclampsia, fetal growth restriction, preterm labor).
Awards and grants
Grants
More than 10 projects have been supported by Federal Target Program of Ministry of Science and Education of the Russian Federation, Russian Foundation for Basic Research (RFBR), Russian Science Foundation (RSF). At the present time, E.A. Trifonova is involved in the following projects:
• “Human population genomics and transcriptomics: search for the signals of non-neutral evolution” (RFBR, 2018-2020).
• “The role of genome regulatory sites in susceptibility to complicated pregnancy” (RFBR, 2018-2020).
Awards
E. A. Trifonova is a Laureate of the Tomsk Oblast Prize in Education, Science, Health and Culture (2017). She was awarded with the Certificate of Honor of the Tomsk city Administration for her great contribution to the development of scientific research, the training of highly qualified specialists and with the Day of Russian Science (2012).
Main Publications
Ekaterina A. Trifonova is the author of more than 80 publications (including 1 book, 2 book chapters, and 60 peer-reviewed papers) and 1 database.
1. Trifonova, E.A., Swarovskaya, M.G., Ganzha, O.A. et al. The interaction effect of angiogenesis and endothelial dysfunction-related gene variants increases the susceptibility of recurrent pregnancy loss // J Assist Reprod Genet. 2019. P. 71-83. https://doi.org/10.1007/s10815-019-01403-2
2. Serebrova V. N., Trifonova E. A., Gabidulina T. V., Bukharina I. Yu., Agarkova T. A., Evtushenko I. D., Maksimova N. R., Stepanov V. A. Detection of novel genetic markers of susceptibility to preeclampsia based on an analysis of the regulatory genes in the placental tissue // Molecular Biology. 2016. V. 50, N. 5. P. 768–776. DOI: 10.1134/S0026893316050162. (https://www.ncbi.nlm.nih.gov/pubmed/27830690)
3. Cherednichenko A.A., Trifonova E.A., Vagaitseva K.V., Stepanov V.A., Bocharova A.V., Varzari A.M., Radzhabov M.O. Prevalence of gene polymorphisms associated with immune disorders in populations of northern eurasia // Molecular Biology. 2015. Т. 49. № 6. С. 881-889.
4. Cherednichenko A.A., Trifonova E.A., Vagaitseva K.V., Bocharova A.V., Stepanov V.A. Association of the genenetic polymorphism of cytokines and their receptors with climate and geographic factors in human populations // Russian Journal of Genetics. 2014. Т. 50. № 10. С. 1112-1116.
5. E. A. Trifonova, T. V. Gabidulina, N. I. Ershov, V. N. Serebrova, A. Yu. Vorozhishcheva, V. A. Stepanov. Analysis of the Placental Tissue Transcriptome of Normal and Preeclampsia Complicated Pregnancies // ActaNaturae. - VOL. 6 № 2 (21). - 2014. – P. 71-83. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115229/).
6. V. A. Stepanov, E. A. Trifonova. Multiplex SNP Genotyping by MALDI–TOF Mass Spectrometry:Frequencies of 56 Immune Response Gene SNPs in Human Populations. Molecular Biology, 2013, Vol. 47, No. 6, pp. 852–862. (DOI: 10.1134/S0026893313060149).
7. E. A. Trifonova, M. G. Spiridonova, T. V. Gabidulina, F. D. Urnov, V. P. Puzyrev and V. A. Stepanov. Analysis of the MTHFR gene linkage disequilibrium structure and association of polymorphic gene variants with coronary atherosclerosis // Russian Journal of Genetics. 2012. V. 48. №10. Р. 1035–1047. (DOI: 10.1134/S1022795412100122).
8. Trifonova E., Eremina E, Urnov F., Stepanov V. The Genetic diversity and structure of linkage disequilibrium of the MTHFR gene in populations of Northern Eurasia // ActaNaturae. 2012. V.4. №1. P. 53-70. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372994/).